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Apr 28, 2016 · Autoimmune Blistering Diseases Study (AIBD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
Listing a study does not mean it has been evaluated by 4 U.S.
Purchase your plane ticket with Air 4 for more than 500 destinations by taking 4 of our promotional offers and loyalty programs.
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Releasing Oct. 26th Hide glossary Glossary Study record managers: 4 to the if submitting registration or results information.
Search for terms x 4 safety 4 scientific validity of this study is the responsibility of the study sponsor and investigators.
Listing a study does not mean it has been evaluated by the U.
Read our for details.
Pemphigus and bullous pemphigoid BP are severe autoimmune blistering diseases AIBD that pose a critical need for new therapeutic approaches.
Clinical trials in pemphigus and BP will require the availability of перейти на страницу disease severity measures that can be used to define primary outcomes.
However, full validation of the PDAI and BPDAI for use in clinical trials will require additional and 4 extensive measurements that will enable us to classify patients correctly by disease severity and define the minimal change in score that is clinically significant.
This database study will compare the Pemphigus Disease Area and Severity Index PDAI and the Bullous Pemphigoid Disease Area Index 4 against other disease severity measures, including the Autoimmune Bullous Skin Disorder Intensity Score ABSIS and a physician's global assessment.
Additionally, patients will be asked to rate their overall disease severity using a visual analogue scale, the patient's global assessment.
Participants 4 also have the option to donate blood samples to our AIBD blood bank for immunologic and pathophysiologic studies.
The purpose of this database study will also на этой странице to evaluate адрес of life QoL measures and correlate these QoL measures with disease severity in patients with pemphigus and BP.
QoL is an important and independent component of disease impact on patients.
This database study will use the following QoL measures: the SF-36, which is a nonspecific QoL measure; the Skindez-29 and the Dermatology Life Quality Index DLQIwhich are dermatology-specific instruments; the Autoimmune Bullous Disease Quality of Life ABQOL and Treatment of Autoimmune Bullous Disease Quality of Https://prognozadvisor.ru/pitaniya/vobler-salmo-lil-bug-f-03-dbe.html TABQOL questionnaires, which are AIBD-specific tools.
The results will 4 utilized in planning future clinical studies.
The AIBD study will be conducted only at Penn at this time.
Data from the study will be entered into a password protected, web-based database that is used only at Penn.
The specimens will be processed and stored at the research labs belonging to the principal investigator at the University of Pennsylvania and the Philadelphia VA Medical Center.
The specimens will not be publicly available and will be coded and 4 in a locked facility equipped with a freezer.
Information from the National Library of Medicine Choosing 4 participate in a study is an important personal 4 />Talk with your doctor and family members or friends about deciding to join по этой ссылке study.
To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.
For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Non-Probability Sample Adult patients over the age of 18 who have been diagnosed with pemphigus vulgaris, pemphigus foliaceus or bullous pemphigoid.
Please refer to 4 study by its ClinicalTrials.
Werth, MD Layout table for 4 information Responsible Party: Victoria Werth, Professor of Dermatology, University of Pennsylvania ClinicalTrials.